https://opendata.uni-halle.de//handle/1981185920/13531 2026-04-08T09:36:44Z https://opendata.uni-halle.de//handle/1981185920/103269 Title: VICTORIA : VIrtual neck Curve and True Ostium Reconstruction of Intracranial Aneurysms Author(s): Berg, Philipp; Behrendt, Benjamin; Voß, Samuel; Beuing, Oliver; Neyazi, Belal; Sandalcioglu, I. Erol; Preim, Bernhard; Saalfeld, Sylvia Abstract: Purpose—For the status evaluation of intracranial aneurysms (IAs), morphological and hemodynamic parameters can provide valuable information. For their extraction, a separation of the aneurysm sac from its parent vessel is required that yields the neck curve and the ostium. However, manual and subjective neck curve and ostium definitions might lead to inaccurate IA assessments. Methods—The research project VICTORIA was initiated, allowing users to interactively define the neck curve of five segmented IA models using a web application. The submitted results were qualitatively and quantitatively compared to identify the minimum, median and maximum aneurysm surface area. Finally, image-based blood flow simulations were carried out to assess the effect of variable neck curve definitions on relevant flow- and shear-related parameters. Results—In total, 55 participants (20 physicians) from 18 countries participated in VICTORIA. For relatively simple aneurysms, a good agreement with respect to the neck curve definition was found. However, differences among the participants increased with increasing complexity of the aneurysm. Furthermore, it was observed that the majority of participants excluded any small arteries occurring in the vicinity of an aneurysm. This can lead to non-negligible deviations among the flow- and shear-related parameters, which need to be carefully evaluated, if quantitative analysis is desired. Finally, no differences between participants with medical and non-medical background could be observed. Conclusions—VICTORIAs findings reveal the complexity of aneurysm neck curve definition, especially for bifurcation aneurysms. Standardization appears to be mandatory for future sac-vessel-separations. For hemodynamic simulations a careful neck curve definition is crucial to avoid inaccuracies during the quantitative flow analysis. 2021-01-01T00:00:00Z https://opendata.uni-halle.de//handle/1981185920/103264 Title: Laparoscopic augmented reality registration for oncological resection site repair Author(s): Joeres, Fabian; Mielke, Tonia; Hansen, Christian Abstract: Purpose Resection site repair during laparoscopic oncological surgery (e.g. laparoscopic partial nephrectomy) poses some unique challenges and opportunities for augmented reality (AR) navigation support. This work introduces an AR registration workflow that addresses the time pressure that is present during resection site repair. Methods We propose a two-step registration process: the AR content is registered as accurately as possible prior to the tumour resection (the primary registration). This accurate registration is used to apply artificial fiducials to the physical organ and the virtual model. After the resection, these fiducials can be used for rapid re-registration (the secondary registration). We tested this pipeline in a simulated-use study with N = 18 participants. We compared the registration accuracy and speed for our method and for landmark-based registration as a reference. Results Acquisition of and, thereby, registration with the artificial fiducials were significantly faster than the initial use of anatomical landmarks. Our method also had a trend to be more accurate in cases in which the primary registration was successful. The accuracy loss between the elaborate primary registration and the rapid secondary registration could be quantified with a mean target registration error increase of 2.35mm. Conclusion This work introduces a registration pipeline for AR navigation support during laparoscopic resection site repair and provides a successful proof-of-concept evaluation thereof. Our results indicate that the concept is better suited than landmark-based registration during this phase, but further work is required to demonstrate clinical suitability and applicability. 2021-01-01T00:00:00Z https://opendata.uni-halle.de//handle/1981185920/103263 Title: Distance and force visualisations for improved simulation of intracranial aneurysm clipping Author(s): Allgaier, Mareen; Neyazi, Belal; Preim, Bernhard; Saalfeld, Sylvia Abstract: Purpose The treatment of cerebral aneurysms shifted from microsurgical to endovascular therapy. But for some difficult aneurysm configurations, e.g. wide neck aneurysms, microsurgical clipping is better suited. From this combination of limited interventions and the complexity of these cases, the need for improved training possibilities for young neurosurgeons arises. Method We designed and implemented a clipping simulation that requires only a monoscopic display, mouse and keyboard. After a virtual craniotomy, the user can apply a clip at the aneurysm which is deformed based on a mass–spring model. Additionally, concepts for visualising distances as well as force were implemented. The distance visualisations aim to enhance spatial relations, improving the navigation of the clip. The force visualisations display the force acting on the vessel surface by the applied clip. The developed concepts include colour maps and visualisations based on rays, single objects and glyphs. Results The concepts were quantitatively evaluated via an online survey and qualitatively evaluated by a neurosurgeon. Regarding force visualisations, a colour map is the most appropriate concept. The necessity of distance visualisations became apparent, as the expert was unable to estimate distances and to properly navigate the clip. The distance rays were the only concept supporting the navigation appropriately. Conclusion The easily accessible surgical training simulation for aneurysm clipping benefits from a visualisation of distances and simulated forces. 2021-01-01T00:00:00Z https://opendata.uni-halle.de//handle/1981185920/103184 Title: Software product-line evaluation in the large Author(s): Lindohf, Robert; Krüger, Jacob; Herzog, Erik; Berger, Thorsten Abstract: Software product-line engineering is arguably one of the most successful methods for establishing large portfolios of software variants in an application domain. However, despite the benefits, establishing a product line requires substantial upfront investments into a software platform with a proper product-line architecture, into new software-engineering processes (domain engineering and application engineering), into business strategies with commercially successful product-line visions and financial planning, as well as into re-organization of development teams. Moreover, establishing a full-fledged product line is not always possible or desired, and thus organizations often adopt product-line engineering only to an extent that deemed necessary or was possible. However, understanding the current state of adoption, namely, the maturity or performance of product-line engineering in an organization, is challenging, while being crucial to steer investments. To this end, several measurement methods have been proposed in the literature, with the most prominent one being the Family Evaluation Framework (FEF), introduced almost two decades ago. Unfortunately, applying it is not straightforward, and the benefits of using it have not been assessed so far.We present an experience report of applying the FEF to nine medium- to large-scale product lines in the avionics domain. We discuss how we tailored and executed the FEF, together with the relevant adaptations and extensions we needed to perform. Specifically, we elicited the data for the FEF assessment with 27 interviews over a period of 11 months. We discuss experiences and assess the benefits of using the FEF, aiming at helping other organizations assessing their practices for engineering their portfolios of software variants. 2021-01-01T00:00:00Z